Which sequence best represents the central dogma of molecular biology?

• A. RNA -> DNA -> Protein
• B. DNA -> RNA -> Protein
• C. Protein -> RNA -> DNA
• D. DNA -> Protein -> RNA

Answer: (B)

The flow of genetic information begins with DNA and is expressed through two main steps: transcription of DNA into RNA, followed by translation of that RNA into a protein. This sequence, DNA → RNA → Protein, shows how genes stored in DNA are first copied into messenger RNA and then used as a template to build proteins. It reflects the direction of information transfer that underlies gene expression in cells. While some viruses use reverse transcription or other routes, the standard pathway for cellular information flow is DNA to RNA to protein, making this the best representation of how genes are expressed.